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Dupuytren's contracture : ウィキペディア英語版
Dupuytren's contracture

Dupuytren's contracture (also known as morbus Dupuytren, or Dupuytren's disease and slang terms "Viking disease" or "Celtic hand),〔Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). Page 989. McGraw-Hill. ISBN 0-07-138076-0.〕 is a fixed flexion contracture of the hand due to a palmar fibromatosis,〔Radiological Society of North America "Radiographics" article "Musculoskeletal Fibromatoses: Radiologic-Pathologic Correlation" at http://pubs.rsna.org/doi/full/10.1148/rg.297095138〕 where the fingers bend towards the palm and cannot be fully extended (straightened). It is an inherited proliferative connective tissue disorder that involves the hand's palmar fascia.〔van Rijssen AL, Werker PM, Percutaneous needle fasciotomy in dupuytren's disease. Hand Surg Br. 2006 Oct;31(5):498-501. Epub 2006 Jun 12.〕 It is named after Baron Guillaume Dupuytren, the surgeon who described an operation to correct the affliction in the ''Lancet'' in 1831.
The ring finger and little finger are the fingers most commonly affected. The middle finger may be affected in advanced cases, but the index finger and the thumb are not affected as frequently. Dupuytren's contracture progresses slowly and is often accompanied by some aching and itching. In patients with this condition, the palmar fascia thickens and shortens so that the tendons connected to the fingers cannot move freely. The palmar fascia becomes hyperplastic and contracts.
Incidence increases after age 40; at this age, men are affected more often than women. Beyond 80 the gender distribution is about even.
==Signs and symptoms==

In Dupuytren's contracture, the palmar fascia within the hand becomes abnormally thick, which can cause the fingers to curl and can impair finger function. The main function of the palmar fascia is to increase grip strength; thus, over time, Dupuytren's contracture decreases patients' ability to hold objects. Patients often report pain, aching and itching. Those patients report pain along with the contractions.
Dupuytren's disease often starts with nodules in the palm of the hand and it can extend to a cord in a finger.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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